GLO1 and Nephropathy: Compared to SHR, SHR-Glo1+/− heterozygotes exhibited increased albuminuria (33.62 ± 0.21 vs. 20.09 ± 4.29 mg albumin/g creatinine, p = 0.03), despite comparable histological findings in both strains (data not shown) indicating incipient nephropathy.