STAT3 and T-cell large granular lymphocyte leukemia: Thus, STAT3 mutations have been reported in between 21% and 73% of TCD8+-LGLL [16,17,19,20,21,22,23,24,25,26] and in 13–70% of CLPD-NK [7,18,21,22,23,24,27], depending on the sensitivity of the approach used.