These differences in the distribution of normal blood-cell subsets among STAT3 mutated (and to a lesser extent also WT T/NK-LGLL cases), were confirmed when T-LGLL and TCD8+-LGLL cases were separately analyzed (including the reduction of B cells only in non-Y640F STAT3-mutated cases), with additional decreased TCD8+-cell and Tγδ+-cell counts among STAT3-mutated total T-LGLL and TCD8+-LGLL cases, and increased CD56++ NK-cell numbers among WT TCD8+ cases (Figure 2A–N and Tables S2 and S3). Here, STAT3 is linked to T-cell large granular lymphocyte leukemia.