STAT3 and T-cell large granular lymphocyte leukemia: Upon comparing the distribution of normal residual T cells of TCD8+-LGLL cases into maturation stages, a similar distribution was observed in blood (Figure S4), except for naïve TCD4+-cell counts—median (range)—that were significantly reduced in both STAT3-mutated—260 (31–1013), p = 0.02—and unmutated—231 (45–755), p = 0.01—patients vs. HD—522 (160–1018) cells/μL.