Interestingly, all above referred normal T/NK-LGL subsets were similarly reduced in monoclonal vs. biclonal STAT3-mutated TCD8+-LGLL patients, except for Tγδ+ cells, which were decreased (p = 0.006) only among STAT3-mutated patients (Figure S3). This evidence concerns the gene STAT3 and T-cell large granular lymphocyte leukemia.