NLRP3 and multiple sclerosis: They isolated exosomes/microvesicles from PDLSCs of patients showing relapsing-remitting multiple sclerosis, the most common form of multiple sclerosis with 85% of occurrence [130], and showed the capability of exosomes/microvesicles to inhibit NLRP3 inflammasome activation, exerting a protective role in experimental autoimmune encephalomyelitis mice model of multiple sclerosis.