In this regard, tiragolumab (Genetech/Roche, South San Francisco, CA, United States) is currently under investigation together with atezolizumab (anti-PD-1) on cervical cancer (NCT04300647), esophageal squamous cell carcinoma (NCT04543617), small cell lung cancer (NCT04256421), NSCLC (NCT04513925, NCT03563716), esophageal cancer (NCT04540211, NCT03281369), advanced liver cancer (together with the anti-VEGF bevacizumab, NCT04524871), urothelial carcinoma (NCT03869190), pancreatic adenocarcinoma (NCT03193190), and advanced metastatic tumors (NCT02794571). The gene discussed is PDCD1; the disease is liver cancer.