Relatlimab (BMS-986016 TSR-022, Tesaro Inc, Waltham, MA, United States) is under investigation in three clinical trials in advanced cancer alone or in combination with anti-PD-1 (NCT02817633, NCT03307785), and in primary liver cancer in combination with anti-PD-1 (NCT03680508). This evidence concerns the gene PDCD1 and liver cancer.