KDM4B and hepatocellular carcinoma: Studies have shown that the knockdown of KDM4B (a H3K9 demethylase) induced HCC growth and metastasis via reduction in miR-615-5p expression and increased RAB24 expression [163], whereas low KDM6B (a H3K27 demethylase) levels in response to miR-941 regulation reduced HCC cell proliferation, migration, and invasion in both in vitro and in vivo [164].