Furthermore, using a myocardial infarction rodent model, Hurt and collaborators demonstrated that capsaicin decreases the infarct area, an effect that was also blocked by capsazepine and by cyclosporine A, suggesting that TRPV1 activation produces protective effects against reperfusion injury in this myocardial infarction model [51]. Here, TRPV1 is linked to myocardial infarction.