SOD1 and metabolic dysfunction-associated steatotic liver disease: Our results showed that the activities of SOD and GSH-Px decreased significantly, while the content of MDA increased significantly in the liver tissue of mice in NAFLD group, indicating an oxidative damage in the liver tissue; the activities of SOD and GSH-Px increased, while the content of MDA decreased in each wogonoside-treated group significantly, suggesting that wogonoside can effectively inhibit the oxidative stress level of liver tissue in NAFLD mice.