Western blot analysis showed that compared with that in the control group, the expression of NF-κB p65 in the liver tissue of mice in NAFLD group increased significantly, while that of IκBα decreased significantly (p < 0.01), and compared with that in NAFLD group, the expression of NF-κB p65 in the liver tissue of mice decreased significantly, while that of IκBα increased significantly in the wogonoside-treated groups (p < 0.01), as shown in Figure 5(d–f). This evidence concerns the gene NFKBIA and metabolic dysfunction-associated steatotic liver disease.