IFIT2 and infection: The recent use of genetically engineered Ifit knockout mouse models have revealed that amongst these Ifit proteins, Ifit2 mostly restricts viral infection and protects mice from severe pathogenesis and mortality following Rabies Virus [11], lethal Vesicular Stomatitis Virus (VSV) [12,13], West Nile Virus (WNV) [14], and Sendai virus (SeV) infection [15].