No significant differences in Epstein‐Barr virus‐encoded RNA positivity (7.0% or 13/186 vs 8.4% or 50/598; P = .5478) or the proportion of double/triple‐hit lymphomas indicating BCL2/BCL6/MYC rearrangements (2.6% or 3/114 vs 1.7% or 6/360; P = .4546) were observed between patients with multiple ENI and those without ENI and with single ENI. This evidence concerns the gene BCL6 and lymphoma.