TLR3 and rheumatoid arthritis: Stimulation of TLR3 with Poly(I:C) ligand along with tumour necrosis factor α (TNF‐α) and IL‐1β in synovial fibroblasts resulted in a cytokine secretome similar to RA synovial fluid, suggesting that the synovial fibroblast contributes considerably to the inflammatory environment at the RA synovial joint [29].