NLRP3 and Hepatic steatosis: Research studies conducted in the NLRP3 murine model have demonstrated that deleting NLRP3 augments WAT browning, lipolysis, hepatic steatosis and impairs wound healing (Stanojcic et al., 2014; Vinaik et al., 2018, 2019), suggesting that inflammatory mediators have beneficial effects in the acute phase post-burn.