Further studies assessing the role of IL6 receptor blockade using Tocilizumab have shown positive results in inhibiting IL6 signaling and attenuating WAT browning and hepatic steatosis in the C57BL/6 murine model after burn injury (Abdullahi et al., 2019b), suggesting the therapeutic potential of Tocilizumab in reducing the WAT-associated hypermetabolic response in burn patients having enhanced IL6 levels. This evidence concerns the gene IL6 and fatty liver disease.