HIF1A and Burkitt lymphoma: In Burkitt lymphoma, in which both MYC and HIF1α are highly expressed, HIF1α can actually collaborate with MYC to induce the expression of specific target genes, such as HK2, PDK1, and vascular endothelial growth factor (VEGF) (Kim et al., 2007) under hypoxia and confer resistance to cisplatin treatment (Nakajima et al., 2019).