The pronounced differences between HS-5 and HS-27A reported in this work is further supported by Li et al. (2013) who showed that HS-27A, differentially from HS-5, can be co-injected in NSG mice with CD34+ cells isolated from myelodysplastic syndrome patients to promote the engraftment of clonal hematopoietic precursor. This evidence concerns the gene CD34 and myelodysplastic syndrome.