Moreover, antibodies against the M and H antigens, a catalase B and beta-glucosidase, respectively, are consistently produced by patients with different clinical forms of histoplasmosis and, therefore, are largely applied in serodiagnostic tests (Pizzini et al., 1999; Guimarães et al., 2004; Almeida et al., 2016; Almeida et al., 2019). Here, TYRP1 is linked to histoplasmosis.