Among all the in vivo protein–protein interactions evaluated for CiLV-C2 and OFV-citrus, the only negative interaction was observed between CiLV-C2 MP and OFV-citrus N, although we have observed interaction between OFV-citrus MP and CiLV-C2 CP, suggesting that the dichorhavirus MP could assist the transport of both cognate nucleocapsid and heterologous capsid proteins in the mixed infection process. This evidence concerns the gene CP and infection.