On the other hand, Forrest et al. have noted pathological variability with specific mutations in MAPT like PSP pathology in S305S, CBD pathology in S305S, IVS10+16 and R406W, PiD pathology in K257T and GGT pathology in P301L, IVS10+16 mutation (176). This evidence concerns the gene MAPT and supranuclear palsy, progressive, 1.