By utilizing whole genome microarray data, a previous genetic study identified two glutamate receptor genes, glutamate receptor ionotropic kinase 2 (GRIK2), and glutamate ionotropic N-methyl-D-aspartate 2B (GRIN2B), were associated with CFS (8). The gene discussed is GRIK2; the disease is myalgic encephalomeyelitis/chronic fatigue syndrome.