Calpainopathy (LGMDR1) was considered a strict autosomal-recessive LGMD-subtype for many years, but patients carrying specific single pathogenic deletion variants in the CAPN3 gene are reported recently showing dominant disease segregation (6, 145), which was not identified in Indian patients in the current study. The gene discussed is CAPN3; the disease is autosomal recessive limb-girdle muscular dystrophy type 2A.