EGFR and breast cancer: Knockdown of ANO1 in MCF-7 or T47D breast cancer cells resulted in a reduced tyrosine phosphorylation of EGFR (the site is not reported) and of STAT3 transcription factor in response to EGF, whereas overexpression of ANO1 in T47D cells increased phosphorylation EGFR and STAT3 (Wang et al., 2019).