PTTG1 and breast carcinoma: Consistent with previous report (Yoon et al., 2012), we showed that the expression of PTTG1 is significantly higher in malignant Hs578T and MDA-MB-231 breast cancer cell lines than that in less malignant SK-BR3 and MCF-7 breast cancer cells and normal breast epithelia cells, as determined by western blot (Figure 1), indicating the involvement of PTTG1 in breast cancer malignancy.