Besides the international guidelines for AD treatment, other recent guidelines, such as Chinese guidelines for the treatment of AD, propose cholinesterase inhibitors and excitatory amino acid receptor antagonist as well as certain traditional Chinese medicines for the treatment of AD (Group Chinese Dementia and Cognitive Impairment Writing Group, Association Special Committee on Cognitive Disorders of the Chinese Medical Doctors Association, 2018). Here, BCHE is linked to Alzheimer disease.