To explore the tumorigenic function of ADFP in vivo, we inoculated ADFP knock‐down NCI‐H1299, ADFP‐overexpressing NCI‐H1299 and their respective control cells into the hypoderm of nude mice, to establish tumour‐bearing mouse models (Figure 3A,E). This evidence concerns the gene PLIN2 and neoplasm.