Furthermore, we compared the levels of NET remnants in RA patients with different ACPA concentration (ACPA‐N, ACPA < 25 U/ml; ACPA‐MP, 25 U/ml ≤ ACPA ≤ 1600 U/ml; ACPA‐SP, ACPA> 1600 U/ml). This evidence concerns the gene PRTN3 and rheumatoid arthritis.