LGALS3 and hydrops fetalis: This was in a line with Kotby, et al. and Meeusen, et al. studies who found that children with HF had a significant elevation of galectin-3 serum level in comparison to controls with mean galectin-3 of (5.75 ± 1.427 ng/ml) at control group (P value ≤ 0.001) compared to mean of (18.40 ± 11.5 ng/ml) at HF patients [19, 22].