For instance, full consistency was achieved for MC1R DNAm site cg01097406 (i.e. all alleles that are associated with fair skin decrease DNAm at this position) and cg07130392, both associated with 7 of the 8 SNPs tested, and for cg08845973 and cg09738481, associated with 6 SNPs. This evidence concerns the gene MC1R and neoplasm.