Table 2 depicts a summary on the distribution of genotypes by menopausal status and hormonal receptor status. The results did not suggest any genetic association between menopausal status and predisposition to BC. No association was detected between ESR1 gene rs2234693 within presence or absence of the estrogen and progesterone hormones and HER2 in tumor samples (Table 2). Here, ESR1 is linked to neoplasm.