MKI67 and infection: An association between p16INK4a/Ki-67 expression and HPV16and18 infection was found in our study with a significant higher positivity rate of p16INK4a and Ki-67 immunohistostaining in HPV16and18 infection group compared to women without HPV16and18 infection (OR: 0.13, 95%IC: 0.03 – 0.52, p<0.0001).