These findings were concordant with previous studies, which found high-level expression status of p16INK4a in high squamous intraepithelial lesions (HSIL) and weak level expression in low squamous intraepithelial lesion (LSIL) (Li et al., 2019; Marjolein et al., 2018; Schiffman et al., 2007). The gene discussed is CDKN2A; the disease is squamous cell intraepithelial neoplasia.