Interestingly, many of the tumour types showed strong +ve and +ve correlation between TC2N genes and genes in common cancer pathways including Myc pathway, cell cycle pathway, p53 pathway, Nrf2 pathway, Wnt pathway, Hippo pathway, TGFβ pathway, Notch pathway, PI3K pathway and RTK/RAS pathways. This evidence concerns the gene TGFB1 and cancer.