Amongst the tumours with low overall TC2N expression, THCA showed significant downregulation of TC2N in all histologic subtypes compared to controls while in PCPG only Paraganglioma;extra adrenal pheochromocytoma subtype showed significant downregulation of TC2N compared to the controls (Table 1). This evidence concerns the gene TC2N and adrenal gland pheochromocytoma.