Of the 10 proteins identified as functional TC2N partner, significant +ve correlation was observed between TC2N mRNA expression of CATSPERB, CELEC4M, SCARA5, SMEK1,SMEK2, STX2 and STXBP5 in pan-cancer (cumulative correlation), further suggesting that these proteins partner with TC2N in it’s signaling pathways (Figure 5). The gene discussed is STXBP5; the disease is cancer.