AML patients have TLR2 (Arg753Gln) GG genotype had the shortest OS; followed by those have AG and GG genotypes (P=0.001) (Figure 1); while TLR4 (Thr399Ile and Asp299Gly) polymorphism did not affect the OS (P=0.06; 0,104 respectively) (Figures 2 and 3). Here, TLR4 is linked to acute myeloid leukemia.