TLR4 and acute myeloid leukemia: Moreover; the studies on the DFS revealed that AML patients have TLR2 polymorphic AA genotype(P=0.002) and those who have TLR4 Thr399Ile CC genotype have the longest disease free survival as compared to the other genotypes CT; TT ; while TLR4 Asp299Gly didn’t have an impact on OS .