A total of 70 patients with CRC and 50 control healthy matched in the population were genotyped successfully for 5 SNPs of AKT1 (rs1130214G/T, rs10138227C/T, rs3730358 C/T, rs1000559097G/A, rs2494737A/T), and for two SNP of LMTK3(rs8108419G/A, rs9989661A/G). The gene discussed is LMTK3; the disease is colorectal carcinoma.