EYS and retinitis pigmentosa 1: Since the first description of the pathogenic effect of EYS variants on RP in 200829,30, many studies have revealed the prevalence of EYS-associated RP in patients with various ethnicities: 15.9% AR traits among those in Spain31, 12% sporadic or AR traits in those from France32, 11% in UK and China33, 10% in Germany , 9.1% in Korea34, 7% in Israel35, 5% in The Netherlands36, and 0% in Northern Ireland9.