Besides, we found many cancer-associated pathways highly enriched in immunity-high, including ECM-receptor interaction, focal adhesion, MAPK signaling, cell cycle, p53 signaling, VEGF signaling, glycolysis, adherens junction, and PPAR signaling (Fig. 5a), suggesting a positive association between these cancer-associated pathways and glioma immunity. Here, PPARA is linked to central nervous system cancer.