LncRNA ZFAS1 accelerates the EMT process via the induction of ZEB1 expression, while knockdown of ZFAS1 upregulates the expression of E-cadherin and ZO-1, but decreases that of ZEB1, vimentin and N-cadherin in colon cancer cells [83]. The gene discussed is CDH2; the disease is malignant colon neoplasm.