By binding with the identified targets, LF triterpenoids could inhibit ErbB signaling pathway, MAPK signaling pathway, PI3K/Akt signaling pathway and VEGF signaling pathway, then inhibit cancer cells proliferation, and induce the cell cycle arrest and apoptosis (Fig. 8), which could explain the result of our previous research [6]. The gene discussed is PIK3CG; the disease is cancer.