In our enrichment analysis, P53 was also upregulated, consistent with the conclusion of Dianov et al. Although the relationship between abnormalities in the BER pathway and the development and prognosis of cancer has been studied [19–21], in pancreatic cancer, whether IGF2BP2 is associated with this process has not yet been elucidated. This evidence concerns the gene TP53 and familial pancreatic carcinoma.