The highest levels of cytokines G-CSF, MCP-1, IFN-γ, IL-1RA, IL-6, IP-10, M-CSF, IL-2, IL-1A, and TNF-alpha were observed in the sickest ICU-admitted COVID-19-(+) patients #2 and 103. The gene discussed is CXCL10; the disease is COVID-19.