In the COSMIC database (Catalog of Somatic Mutations in Cancer) several mutations in the HABP4 gene were found, being the intestine (13%) and related digestive tract tissue cancers (additional 30%; stomach, upper aerodigestive, pancreas, oesophagus, liver) the tissues with the highest incidence of mutations (43% total) (Figure 4). The gene discussed is HABP4; the disease is cancer.