Furthermore, the amino acid sequence of HABP4 is rich in charged amino acids and the protein seems to be part of the family of so called IUPs (intrinsically unstructured proteins) [27], proteins which are known to have many interactors, frequently with regulatory functions, that tend to occupy hub positions in complex protein networks and are frequently described for their involvement in cancer related cellular processes [33]. This evidence concerns the gene HABP4 and cancer.