The first concrete link that suggested some relevance of HABP4 in cancer was soon after it ́s cloning [9], when FISH experiments showed that the gene of HABP4 is located in region 9q22.3-3.1 of the chromosome 9 that had been reported as a hot spot for secondary aberrations in acute myeloid leukemia. The gene discussed is HABP4; the disease is cancer.