To assess the HABP4 expression profile in colon and liver tissues, immunohistochemical assays were performed with commercially available slides containing 20 normal colon tissues, 156 malignant tissues (125 adenocarcinoma, 28 mucinous adenocarcinoma and 3 papillary adenocarcinoma), and 3 normal liver tissues and 5 tumor liver tissues in response to colon metastasis. This evidence concerns the gene HABP4 and papillary adenocarcinoma.