As shown in Figure 1, the cancer-derived cells U251 (Figure 1A) and SUPT1 (Figure 1B), when treated with anti-apoA-1 IgGs for 48 and 72 h, presented the typical hallmarks of apoptosis: rounded and shrinked cells, detachment from the flask for U251, retraction of the nucleus with chromatin condensation, emission of apoptotic bodies. Here, APOA1 is linked to cancer.