Recent studies have shown that circHIAT1 the metastasis inhibitor inhibits the migration and invasion of androgen receptor-enhanced renal cell as well as carcinoma cell, and it also increases the expression of circHIAT1 to target androgen receptor inhibition, thereby inhibiting the invasion and migration capabilities of renal cell carcinoma [19,20]. The gene discussed is AR; the disease is hereditary clear cell renal cell carcinoma.