LEPR and polycystic ovary syndrome: Table 2 lists the characteristics of the three genotyped LEPR SNPs. Marginal departure from HWE was noted for rs1137100 in Bahraini (P=0.04) and rs1137101 in Tunisians (P=0.01). The distribution of the minor alleles of rs1137100, rs1137101, and rs2025804 in Tunisian and Bahraini women with PCOS and control women are shown in Table 3. Significantly lower rs1137100 (P=0.008) and higher rs1137101 (P<0.001) MAF was seen in Bahraini women with PCOS compared with ethnically matched controls, which persisted after the Bonferroni correction for multiple testing.