It has been reported that the addition of cisplatin to cervical cancer cell cultures induced IL-17E and IL-17RB down-regulation, eventually inhibiting in vitro growth, migration, and invasion (169), Thus, IL-17E might exert a tumor-promoting activity, unless the latter depends on IL-17B, which also interacts with IL-17RB. The gene discussed is IL17RB; the disease is neoplasm.