IL-6 is a pro-inflammatory cytokine that contributes to the development, progression, and severity of CRS as well as its complications, including disseminated intravascular coagulopathy (DIC) and multi-organ failure (Chen et al., 2020; Huang et al., 2020; Uckun, 2020b; Young et al., 2019; Zumla et al., 2020). Here, IL6 is linked to congenital rubella syndrome.