TGF-β has been implicated as an important pro-inflammatory cytokine in the pathophysiology of acute lung injury and ARDS (Pittet et al., 2001; Fahy et al., 2003; Frank and et al., 2003; Willis and et al., 2003; Jenkins and et al., 2006; Frank and Matthay, 2014). The gene discussed is TGFB1; the disease is acute respiratory distress syndrome.