Using Cre recombinase driven by the promoter of Amhr2, we generated mice with the genotype Ptenfl/fl KrasG12D/+ Amhr2-Cre (G12D mice) or with Ptenfl/fl KrasG12V/+ Amhr2-Cre (G12V mice), in which different types of gynecologic tumors developed (Fig. 2 and Supplementary Fig. S1). Here, AMHR2 is linked to female reproductive system neoplasm.