Because we had generated a low-grade serous ovarian carcinoma mouse model with the Amhr2-Cre Pten(fl/fl) KrasG12D/+ genotype (G12D mice) for a previous study30,31, we decided to generate mice with the Amhr2-Cre Pten(fl/fl) KrasG12V/+ genotype (G12V mice) for the present prospective investigation. This evidence concerns the gene PTEN and ovarian serous carcinoma.