Vimentin is one of the most commonly used markers for EMT, and a large number of studies have reported that vimentin is closely related to cancer metastasis.1–5 In addition, matrix metalloproteinases (MMPs), such as MMP-1, 2, 3, 6, 9, and other members, are considered as the major proteolytic enzymes that hydrolyze matrix components and destroy tissue barriers to promote cancer metastasis. Here, VIM is linked to cancer.