Results from studies investigating the associations between level of activity and glucose metabolism in general have varied.5 11 12 14 For stroke in particular, Moore et al found an association between energy expenditure and glucose and insulin sensitivity (HOMA), not adjusted for BMI, age, DM or medication use.23 Beyond that, high quality studies on the impact of sedentary behaviour in the stroke population are scarce. This evidence concerns the gene INS and Stroke.