For example, Liu et al. employed miRNA microarray analysis to identify a total of 32 differentially expressed (DE) miRNAs accompanied by 23 miRNAs up-regulated and 9 miRNAs down-regulated in keloid, which were closely associated with TGF-β, MAPK, apoptosis, and cell cycle signaling pathway [28]. This evidence concerns the gene TGFB1 and keloid.