TP53 and bladder transitional cell carcinoma: Although there was no significant difference between them (p > 0.05), probably due to the small sample size in this cohort, the overall trend of the median MATH values showed that MATH values were greater in BLCA patients with TP53 mutations than in those with FGFR3 mutations (Fig. 6a, p = 0.074) and MATH values were lowest in BLCA cases with FGFR3 mutations (Fig. 6a), consistent with our findings in the TCGA BLCA cohort (Fig. 5a).