PXN and acute monocytic leukemia: In addition, human acute monocytic leukemia cells (THP-1) stably expressed the short hairpin RNAs (shRNAs) against Paxillin (sh-Paxillin) were generated by infection with sh-Paxillin-Lentivirus and the short hairpin RNA (shRNA) against GFP (sh-NC) were generated by infection with sh-NC-Lentivirus.