Collectively, most studies have demonstrated that SNHG15 is involved in gene regulation by acting as an oncogene in various malignancies, and its elevated expression might be associated with the prognosis and clinicopathological parameters of gastric cancer, hepatocellular carcinoma, lung cancer, non-small cell lung cancer, renal cell carcinoma, pancreatic ductal adenocarcinoma, breast cancer, papillary thyroid carcinoma, colorectal cancer, and epithelial ovarian cancer [21–31]. The gene discussed is SNHG15; the disease is differentiated thyroid carcinoma.