The association of ACE2 gene polymorphisms with various cardiovascular disease phenotypes (hypertension, left ventricular hypertrophy, coronary artery disease and myocardial infarction), as well as Type 2 diabetes (T2DM) and pulmonary disease, has been the subject of several studies, with conflicting results [13]. The gene discussed is ACE2; the disease is type 2 diabetes mellitus.